Borgdorff - Epidemiology Of Hiv-i Infection In Mwanza Region, Tanzania

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HIV-1 infection is the leading cause of death in the Mwanza Region of Tanzania. This area is the site of the Tanzania-Netherlands research project on HIV infection in the region, for which the author was the project leader. The studies presented here cover the epidemiology of HIV-1 infection in adults in Mwanza Region.<br />A population survey showed that HIV-1 infection affected 2.5% of the adult population in rural villages, 7.3% in roadside settlements and 11.8% in town, and was 1.5 times more common in women than in men. Results of the population survey were used to validate HIV-1 surveillance systems, and to show that HIV-1 infection was a risk factor for the development of tuberculosis and leprosy. In a factory cohort study, new HIV-1 infections occurred at a rate of 1.2% per year, and 62% of deaths were attributable to HIV-1 infection. Sexual partner change was common in this cohort and condom use extremely low.<br />This book will be of particular interest to those involved in AIDS control and surveillance, and to epidemiologists concerned with the spread of HIV infection and its natural history.